Report No 23 -------------------------------------------------------------Fall, 2001
Selenium - the micro-nutrient that can have a major role to play in the prevention and treatment of Hepatitis, AIDS and cancer.
Self-defense against Anthrax and Bio-terrorism
Selenium deficiency linked to HIV progression, falling T cell counts, cancer and heart disease ¨
Our memories are fresh from the tragic events of that fateful day - 9/11/01. It parallels another tragedy that that left a nation in shock and disbelief - the assassination of President John Kennedy on November 22, 1963, an event I remember vividly.
Since the tragedy of 9/11, the mailing of Anthrax spores through the US Postal Service as well as the hijacking of a Greyhound bus, which left 7 people dead, leaves us to realize how vulnerable we are living in an open society that is now being targeted by a handful of foreigners who hate America and Americans. The smoldering fires of the Israel/Palestinian conflict have reached our shores.
The recent acts of terrorism are linked not only to the Israel/Palestinian conflict but Mideast politics as well as radical interpretations of the Islamic Koran by extremists like Osama Bin Laden and his followers. The conflict between Israel and the Palestinians, that has been going on for far too long, clearly requires outside intervention..
What is needed is a neutral military force, perhaps the United Nations, to separate the warring factions so they stay out of each others territory and stop the killing. A Palestinian state needs to be created and the borders that Palestine and Israel share need to be patrolled by neutral countries under the auspices of the UN.
The US urgently needs to exert more influence over the peace process and push it forward until it reaches a conclusion even if the final status of Jerusalem is not resolved. Meanwhile, politics aside, many Americans are wondering if Anthrax has arrived in their mailbox and how to protect themselves from accidental exposure. Inhalation Anthrax has already killed 4 people.
It is possible that some Americans other than postal workers, government officials and members of the media have been infected with Anthrax on the outside of envelopes. Regular Americans are not the target of the Anthrax mailings thus far. There is also the fear that terrorists may have small pox cultures to unleash on us. If this infectious agent is ever released, it could spread worldwide and kill over a billion people on the planet. Potentially, the impact of unleashing small pox could be as deadly as a nuclear war or an asteroid collision with the earth.
Almost any common disinfectant kills the strain of anthrax currently being mailed. Recently, it has been determined that some of the spores are ground finely enough to pass through a porous envelope and infect a person touching the envelope. Until the government finds and stops whoever is responsible for the Anthrax mailings, you may want to consider stocking and using the following items:
1. Throw away plastic gloves. (Use to pick up mail)
2. Lysol or Clorox disinfectant sprays cans. (Spray inside of mailbox daily)
3. Lysol or Clorox disinfectant pre-moistioned wipes in a jar. (Wipe outside of mail without damaging contents inside).
The above three items can be found at most grocery stores. Other defenses against bio-terrorism include 3% hydrogen peroxide, Clorox bleach, Ozone, Colloidal Silver in a nasal spray bottle (Source Naturals). This fine colloidal silver with no added acids or other minerals is mild and gentle and may be inhaled up the nostrils and even directly in the lungs.
Some other colloidal silver products are made with acids and other minerals added and are only intended for oral consumption and would be very irritating if inhaled.
For small pox, soak in half a bathtub of water with 12 pints of 3% H2O2 added for 30 minutes once a day. If the condition does not clear up in a few days, take some H2O2 sublingually, under the tongue about 1 teaspoon of the solution every 30 to 60 minutes. For Anthrax, you will need to take antibiotics prescibed by your physician.
For inhalation Anthrax, inhale a mist of colloidal silver for a couple minutes 4 or 5 times daily for the first 5 days while taking the antibiotics. Always check with your physician and inform him or her of any self-treatment or medications you are using.
Note: a negative ionizer in the house of office can stop the spread of airborne pathogens as the negative ions will electrocute the pathogens and precipitate them out of the air. UV light also kills anthrax. For more information on Anthrax, go to - www.cdc.gov or www.hhs.gov
Selenium is a trace element that is well known for its antioxidant properties. It has a physical structure similar to sulfur. In plants, it has an affinity to bind to sulfur-based proteins like methionine or cysteine. I have reported on selenium in past issues of this newsletter because it is an antioxidant and supports the bodys main antioxidant and immune stimulant - L glutathione. This issue makes selenium the centerpiece story because of extraordinary lab results in two cases where persons, who had hepatitis C, credit selenium with reducing the viral load by 87% in one case and 94% in another.
What makes these two cases unique is the dosage used, 1200 mcg daily in the first case and 1000 mcg daily in the second. These amounts are higher than the usual RDA of 70 mcg. Most dietary supplement manufacturers advise consumers not to use over 200 mcg or 400 mcg daily due to concerns of side effects or adverse effects from too much selenium.
In April or May, I received an email that reported on a location in Africa where the selenium content in the soil was high and in this location, there was very little HIV or AIDS. The writer suggested a correlation between the selenium content n the soil, and thus in the food and diet, and very few AIDS cases in that location. I remember that without investigating the email message further, I deleted it from my computer and my attention was directed elsewhere.
At the time, our email inbox was being overrun with SPAM, unsolicited advertising. Hundreds of these unsolicited emails would arrive weekly so often I would make a 10 second or less snap decision on whether or not to save an email message. The email message on selenium vs. AIDS was one I had deleted in haste. Finally, in June, we changed our email address to email@example.com and things have really quieted down as far as email volume is concerned. In the process, a couple thousand messages, some with useful information in them, were deleted.
Researchers have found that Glutathione is a crucial antioxidant that inactivates many kinds of free radicals, but also supports antigen processing inside cells and thus helps with cell-mediated immune responses. Selenium along with Cysteine are the best known precursors to increasing Glutathione production in the body. Selenocysteine and L-selenomethionine are two forms found in Brazil nuts, fish, yeast and other natural sources. Riboflavin, or Vitamin B2, is reported to help recycle oxidized glutathione back to its reduced form. Vitamin E is reported to help with the assimilation and utilization of selenium. (Note: Selenium Synergy, from Jarrow Formulas, contains added Vitamin E and B2 along with the natural yeast derived form of L-selenomethionine).
Besides selenium, Alpha Lipoic Acid (ALA) and Silymarin (Milk Thistle) are two additional dietary supplements that support glutathione activity and protect the liver. L Glutamine and cold processed whey proteins like ImmunePro enhance Glutathione activity due to the undenatured L cysteine contained in the product. Lab results indicate that ImmunePro, a cold processed whey protein, also contains 170 mg of Lactoferrin per 5 gram serving, a significantly high lactoferrin content. Lactoferrin binds to iron and thus blocks viruses from using iron to replicate.
Published literature indicates that as the Glutathione levels increase, the HIV and hepatitis viral loads decrease. The extent of the decrease in viral load may well depend on how much Glutathione is available inside the cells. Understanding the subject of Glutathione can become complex as medical writers refer to various Glutathione compounds.
According to Regina Brigelius-Flohe of Potsdam, Germany, the family of glutathione peroxidases comprise 4 distinct selenoproteins. They are cGPx, GI-GPx, pGPx and PHGPx. All 4 types of Glutathione are called selenoproteins because they incorporate selenium into their molecular structure. Selenium is also involved in several other proteins in people and have various functions other than as an antioxidant. About 30 types of selenium bound proteins have been detected in mammals and may well exist in humans as well.
Selenium for HCV: Rare is an over-the-counter treatment for HCV or HIV that reduces the viral load up to 94%. The rarity of such an event did occur in July, 2001. Late in June, 2001, Jose of San Paulo, Brazil, had immunized 5 chickens by injecting a few drops of his blood subcutaneously under their skin. He did this to challenge the chickens immune system with his HCV. The end result is that immune factors would end up in the eggs laid by these chickens. Starting in July, he would eat daily a couple of these raw immunized eggs from these chickens as a treatment for his HCV.
In his email message in July, he reported symptomatic improvement and a small decline in HCV viral load. But what he wrote about selenium, almost as an after thought, caught my attention. Selenium has now become an important story driven by extraordinary lab results.
I had a viral load of 1.5 million or log 6 when I was first diagnosed 3 years ago. I started on a high selenium dose intake of 1200 mcg daily which I did for 5 days. The viral load dropped from 1.5 million to 200,000 and has stayed there since. 200,000 is low for HCV by NIH Hepatitis Consensus Conference.
I havent taken the viral load very often for HCV as I consider the enzyme levels to be a more important indicator of the health of my liver. No elevated enzymes means no inflammation and no damage to the liver regardless of the viral load. I have seen people with HCV viral loads over 5 million and with normal liver enzymes. Also, I have seen people with low viral loads and high enzymes and resulting damage to the liver.
I dont consider the 200,000 viral load of last year to be a reliable baseline as it was done so long ago. The best I can do is to look at the 150,000 viral load, after using the eggs for 2 + weeks, as a baseline and see what happens in the next few months when I am retested.
I still think the hyper-immunized eggs I have been using are superior to many other treatments I have tried. Jose
Jose also reports his wife has the same viral type of HCV that is 1a. He says she cannot take the eggs every day because she has gall stones and the egg yolks cause discomfort and bad digestion. Besides the reaction seems stronger with her with lots of running nose, head aches and low grade fevers. Jose: firstname.lastname@example.org
Note: An article I read some time ago reports that pure lemon juice will dissolve gall stones eliminating the need for surgery in many cases. The article suggested about 1/4 cup of lemon juice mixed with an equal amount of water and taken on an empty stomach twice daily. The article was from a book on Chinese remedies but I dont recall the title or how many days you had to do this to dissolve the stones, but I thought it was just a few days. Some readers have reported gall stones have been eliminated from their gall bladder with the daily or twice daily use of the whole lemon/olive oil drink.
Update: Jose sent an email message in which he stated that after 45 days of using 1200 mcg daily of selenium, he reduced the dose to 200 to 400 mcg daily for the past two years. Recently, he increased the dose to 600 mcg daily.
My first reaction is reading Joses email message was that while the immunized eggs had helped reduce his viral load for HCV from 200,000 to 150,000, the results he had earlier with the selenium were far more impressive. Incredible results, but what about side efffects?
Who ever heard of anyone taking 1200 mcg of selenium daily? Wasnt this dangerous? I realized that I needed to do some basic research into selenium levels and the dosages that give benefits or cause side effects.
The following month, August, I received an email from another reader with hepatitis C who shared his experiences with 1000 mcg of selenium daily for one year. This time, his message and the results he obtained captured my attention - big time.
Let me preface my thoughts by saying that the current minimum RDA for Selenium in the US is around 70 mcg daily for adults. The typical dose in dietary supplements is about 200 mcg daily. I have read that selenium from dietary sources alone range from near zero to a high of 1100 mcg daily, depending on where you live and the amount of selenium found in the soil and eventually in the food. So far, we can assume that selenium levels vary widely among the populations of the world.
While in normal individuals, over exposure to selenium may be toxic causing gastrointestinal problems, hair loss and nerve damage, in persons with AIDS or hepatitis whose selenium levels are usually depleted because of the disease process, the normal and safe levels are thought to be much higher than the 200 to 300 mcg used daily by normal healthy individuals.
Contrary to conventional wisdom, I have supplemented with selenium at 1000 mcg daily with occasional lapses for over a year now without any noticeable ill effects, other than faster than normal hair and nail growth. During this time, Ive seen my viral load for HCV drop from over 10,000,000 to around 600,000 along with a corresponding improvement in my overall condition. Cliff------------email: Kudos25@aol.com
The letter from Cliff arrived a few weeks after the letter from Jose. It was the letter from Cliff that caused me to sit up and take notice. I was now motivated to sink my teeth into some serious research on selenium. I thought, from 10 million to 600,000 is a 94% drop in viral load. These kind of results are impressive as no side effects have been reported either. The cost is low and no prescription is needed. What would 1000 mcg of selenium daily do to an HIV viral load? How about HHV-6?
In 1996, Dr. David Ho introduced the now famous triple drug cocktail with protease inhibitors at the 11th Intl Aids Conference in Vancouver. However, many physicians writing prescriptions didnt stop with 3 drugs. They increased the number to 4, 5 or even 6 for a combination cocktail to reduce viral loads to non-detectable levels. At the same time the drug combinations began to cause toxic side effects. Five years after Vancouver, the side effects are mounting with recent reports of an increase in AIDS-related deaths. Many of these are from a variety of causes like heart failure and liver failure and AIDS is not always listed by physicians as the cause of death.
The September issue (2001) of POZ magazine is called The Death Issue. It reported on many of these deaths from persons HIV+ that are not actually being recorded as AIDS-related as they are not due to traditional AIDS related infections like PCP, MAC or KS but are due to liver failure or heart disease most probably caused by the toxic effects of too many drugs for too long. Reality sets in, in that success cannot measured by viral load counts alone when persons being treated are dying from liver failure or heart disease. After all, a funeral is a funeral is a funeral.
Restoring sanity in treating persons affected by HIV/AIDS requires finding and testing a friendlier cocktail that has fewer side effects and preferably none at all. Using fewer drugs and/or strategic interruption drug protocols will produce fewer side effects. The idea of combining an effective non-toxic treatment like selenium with 2 drugs instead of a smorgasbord of drugs is an idea whose time has come. Who will step up to the plate and furnish the funding for such a study? If this approach is successful, the cost of treating AIDS patients and the accompanying side effects could decline by 50 to 75% or more. While this may not yet be a cure, it is very significant progress. Besides a leaner and friendlier cocktail, the use of planned strategic interruption of the drugs could reduce side effects up to 99% or more while maintaining efficacy as a treatment.
I see no reason why someone who has a non-detectable viral load and a CD4 count over 200 could not use the drugs every other month which would leave them free from drug therapy 6 months out of the year. In the off months, they could and should still use selenium and other immune modulators (Maitiake, shiitake, garlic, zinc, transfer factor, beta glucans and more). Medicaid should pay for these over the counter supplements.
On choosing two drugs, take your pick of two that complement each other like Zerit and Epivir. Of the 15 of so FDA approved drugs for HIV, the worst side effects being reported by our readers are from DDI, Ziagen (Abacavir), Combivir, Trizivir, and AZT.
Note: AZT is contained in both Combivir and Trizivir. All three drugs are Glaxo-Welcome products.
Selenium: I would use a natural form bound to an amino acid like L selenomethionine (yeast derived) rather than sodium selenite. A formula to determine a therapeutic dosage level is 100 mcg (or more) per 20 lbs of body weight. Example: 180 pound person - divide 180 by 20 = 9. Take 9 times 100 = 900 mcg of Selenium daily.
When testing for selenium levels in the blood, be aware that amounts above 800 mcg per liter of blood are associated with minimal side effects (hair loss and loose finger/toe nails) while strokes and heart attacks occur when selenium levels drop below 45 mcg per liter of blood. Based on a reasonable reading of published research, a good therapeutic dosage level to aim for is 300 to 600 mcg per liter of blood and that being a suggested therapeutic level for persons with HIV/AIDS, hepatitis, cancer, CFIDS, heart disease and chronic infections including Lou Gerigs disease.
Note: Blood tests can monitor selenium levels. Even though some blood tests have found selenium levels as high as 3200 mcg per liter in humans, no case of liver toxicity can be found anywhere in the medical literature. In animal studies, side effects start to occur around 600 mcg of selenium per liter of blood in sheep who are sensitive to selenium while side effects occur in cattle only at much higher levels. In humans, minor side effects like loose hair or hair falling out are conditions that are reversible when selenium supplementation is interrupted.
A substantial amount of published scientific research has linked selenium deficiency to AIDS progression, increased HIV replication, weight loss, heart disease and elevated beta2 microglobulin levels. Supplementation with selenium has been reported to increase interluken 2 levels, increase T cell counts, reduce tumor necrosis factor, reduce the risk of cancer, reduce HIV replication, reduce beta2 microglobulin levels (measures rate of cell destruction), reduce depression and decrease the risk of death from HIV infection. (1, 2, 3, 4, 5). Selenium also is reported to help increase thyroid hormone production. (6). In AIDS, selenium deficiency has been linked to weight loss, heart disease and poor prognosis for toxoplasmosis.(7).
Richard Passwater first published his research on selenium in the December, 1971, issue of Prevention magazine and has been researching the benefits of selenium ever since. His 48 page book Selenium Against Cancer and Aids is published by Keats Publishing and is found in health food stores. In reading through his book and in a partial review of hundreds of scientific abstracts and references to over 600 scientific studies, here is a useful but incomplete summary of what I have learned.
1. reduces mutations among viruses and other pathogens.
2. Increases glutathione peroxidase levels, the main antioxidant that our cells use to protect us from free radicals.
3. helps prevent most types of cancer including prostate cancer.
4. is used to produce an enzyme that helps the thyroid convert the hormone T4 to T3. (may help normalize body temperature)
5. low levels have been associated with depression and schizophrenia.
6. reduces the toxic effects of mercury and cadmium in the body.
7. protects the liver
8. improves cell mediated immune responses by helping with antigen processing inside cells.
9. helps cellular respiration.
10. works synergistically with vitamin E in preventing cancer.
11. At therapeutic doses, reduces HIV and Hepatitis viral replication and helps shrink cancers.
12. levels of selenium have been found to be subnormal for all types of cancer tested.
1. J Infect Dis. 2000 Sep;182 Suppl 1:S69-73
2. J Assoc Nurses AIDS Care. 2000 Mar-Apr;11(2):103
3. J. Neurovirol. 1998 Jun 3-6;4(suppl):343
4. Conf Retroviruses Oppor Infect. 1996 Jan 28-Feb1;3rd:122
5. Annu Conf Australas Soc HIV Med. 1997 Nov 13-16;9:133
6. Lancet. 2000 Jul 15;356(9225):233-41
7. Int Conf AIDS 1996 Jul 7-12;11(1):124
Q: What is the normal level of selenium in the blood?
A: A realistic average from multiple sources is 180 mcg/liter plus or minus 90. Cancer, AIDS and hepatitis patients usually have low levels - less than 100 mcg/liter of selenium in the blood. (Researchers have found that persons with less than 45 mcg/liter are at high risk to get a stroke or heart attack.). A therapeutic dosage range starts at 180 mcg/l and goes up to 600 mcg/l.
Q: What is the RDA for selenium?
A: The RDA is rated at 70 mcg per day for adults but this is way too low an amount for preventing cancers or to stop AIDS progression. In the United States, diet alone provides about 100 mcg daily. In the UK, the average daily intake is 60 mcg. In Japan, where selenium rich seafoods are consumed and cancer and AIDS are substantially lower than in the US and the life span is considerably longer, the average intake of selenium from diet is 600 mcg daily.
Q; Is it important to take iodine supplements when consuming selenium at higher dosage levels?
A: Ocean fish are a rich source of selenium and are also high in iodine. This is important as research in Africa in persons with stunted growth (cretinism) from thyroid malfunction and who were deficient in iodine and also took selenium supplements without adding iodine had an even more impaired thyroid function after 2 months. If you are not using iodized salt and do not eat fish or sea vegetables 2 or more times weekly, then taking 2 or more kelp capsules daily as a source of iodine is recommended when using selenium supplements. Persons with low body temperature should use kelp along with selenium.
Q: What about toxicity?
A: Passwater states that organic forms of selenium (i.e. selenomethionine - derived from yeast) may have side effects at a dose over 3,500 mcg daily while inorganic forms like sodium selenite may have side effects at 1200 mcg or more daily. The most common symptom is hair falling out followed by loose toe and finger nails. The symptoms are reversible when dosage is reduced or stopped temporarily. More advanced side effects from higher doses of selenium include gastrointestinal problems and nervousness.
Based on animal studies, an adult would have to consume over 100,000 mcg daily for 3 or 4 weeks to have a fatal overdose. At 100 mcg per capsule, that would be over 1000 capsules daily. In comparison, a handful of iron tablets is enough to kill a healthy child. While medical records report annual deaths from accidental ingestion of iron tablets by children, no case exists in recorded literature of a human death from an overdose of selenium. A very detailed report on selenium and research on toxicity can be found on Toxline at http://toxnet.nlm.nih.gov (3). Conclusion: Selenium is by far a very safe dietary supplement.
Q: If a person is healthy, how much organic selenium should be taken daily as a supplement to prevent selenium deficiency?
A: I think the Japanese consumption level would be a good mark to emulate and that is 600 mcg daily. Passwater reports that in Greenland, many residents consume 1,300 mcg daily with no known side effects.
Q: How much selenium is needed to have a therapeutic effect if you have AIDS, hepatitis or cancer?
A: Our two readers who reduced their HCV viral load up to 94% did it by taking 1000 to 1200 mcg daily or about 100 mcg of selenium per 20 pounds of body weight daily. Vitamin E, about 30 mg per 100 mcg of selenium help with the absorption and utilization of selenium.
Note: Selenium Synergy by Jarrow Formulas contains 100 mcg of L seleno-methionine, 30 mg of Vitamin E, Vitamin B2 and aged garlic extract. B2 (Riboflavin) helps to recycle oxidized Glutathione back to its reduced form.
A good mix is 4 to 6 capsules of Selenium Synergy daily along with 4 to 6 Brazil nuts. This will give you from 600 to 1000 mcg daily of organic selenium.
Q: What foods are highest in selenium?
A: Brazil Nuts have the highest concentration of natural organic protein-bound selenium of any food on the planet.(50 to 100 mcg per nut) followed by brewers yeast, fatty fish (salmon, tuna, sardines), oysters, clams, wheat germ, mushrooms and whole grains.
Note: If you weigh 180 lbs, eating 3 Brazil nuts 3 times daily would give you 450 to 900 mcg of selenium and a therapeutic dose that could be increased under a physicians supervision and monitoring of blood levels. The selenium content of Brazil nuts is not standardized and depends on the selenium content of the soil where the nuts are grown. This is why a range exists from 50 to about 100 mcg per nut.
Note on blood levels: Reduce selenium intake if blood levels go above 600 mcg per liter or when your hair gets thin or starts falling out. Based on current available information, an immediate target goal is to raise selenium blood levels to 300 mcg per liter and then to increase the level up to 600 mcg/liter or until side effects start to occur then to back off a bit until the side effects stop. This should give you the best therapeutic effects in treating AIDS, Candidiasis, Lyme disease, hepatitis, Cancer, Low Gerigs, Chronic fatigue syndrome and other similar conditions.
Stanley Brosman MD and Mark Moyad MD write about Nutrition and Prostate Cancer in the eMedicine Journal (1). Dr Brosman is a Professor at the Department of Urology at the University of California Los Angeles Medical School. The authors have found that the risk of developing prostate cancer in the United States is 204 times greater here than in China.
In a population of 200,000 men, one person will develop prostate cancer in China annually while in the US the number would be 204 each year. The physicians looked for dietary factors that contribute to this difference. They found a higher risk for prostate cancer among persons who eat red meat, are on diets high in fat and or are obese. The researchers found a relationship in the protective effects of selenium peroxidases that repaired oxidized phospholipids and the prevention of oxidation of lipids by vitamin E, hence a synergistic relationship between vitamin E and selenium.
A study by Clark et al (2) demonstrated a 50% decrease in cancer mortality and in the incidence of prostate cancer in men who took 200 mcg daily of selenium versus a control group taking a placebo. Another study on the effects of 200 mcg of selenium found no effects on skin cancer but found a reduction in breast cancer and prostate cancer.
1. eMedicine Journal, July 19, 2001 Vol 2, No 7
2. Clark LC et al; Decreased incidence of prostate cancer with selenium supplementation... Br J Urol 1998 May;81(5): 730-4 (Medline)
3. WHO working group: TA: Environmental Health Criteria PG:306 p YR:1987 IP: VI:58. Can be downloaded from www.toxnet.nlm.nih.gov. Search the phrase selenium toxicity
Dr. BM Berkson of the Integrative Center of New Mexico reported in a German medical journal (Med Klin) in October, 1999, of the results of treating 3 patients, who needed liver transplant surgery, with a triple antioxidant therapy. The therapy consisted of therapeutic doses of alpha lipoic acid, silymarin and selenium. Dr. Berkson stated that interferon therapy works about 30% of the time and that even with liver transplant surgery, residual hepatitis C virus will infect and damage the new liver.
Dr. Berkson states that the antioxidants, alpha lipoic acid, silymarin and selenium have antiviral, antioxidant and free radical scavenging properties. Berkson treated 3 patients who had cirrhosis of the liver and portal hypertension and reported that they recovered quickly, did not need liver transplants, and have all returned to work and are feeling healthy. A major factor in the success of this therapy probably was the dosage that was used which consisted of 600 mg of Alpha Lipoic Acid, 400 mcg of selenium and 900 mg of silymarin (milk thistle extract) daily in two or three divided doses. Dr. Berkson can be reached in NM at his clinic at 505-524-3720. The full article can be found at www.nationalhepatitis-c.org/newswinter2000
In researching the published medical lierature, I found other sources recommending 600 mg daily of ALA for chronic liver disease and no reports of side effects from this much Lipoic acid. Also, for Silymarin, No reports of side effects from high doses of 900 mg daily for adults.
Selenium and glutathione levels decline as AIDS progresses according to Look MP et al in the 1997 European Journal of Clinical Nutrition (1). Is stage I of HIV infection, selenium levels in the blood were an average of 82 mcg per liter. Even in Stage I, the selenium levels are below the minimum of 85 mcg/l considered the least amount needed to maintain health.
In Stage II, the selenium levels dropped to an average of 68 mcg and in Stage III, selenium levels dropped to 51 mcg/liter. Researchers found that selenium levels correlated positively with CD4 counts and inversely with levels of tumor necrosis factor receptors type II. They found that in persons with both HIV and HCV, the selenium levels were the most depressed. Hence, this latter group is in urgent need of selenium supplementation.
In a study published in The Lancet(3), it was found in Finland that when selenium levels were less than 45 mcg per liter of blood, there was an increased risk for strokes and heart attacks. In another study in men, the risk factor was 3.7 times higher for strokes and heart attacks in men whose selenium levels were less than 45 mcg/l. (4)
Baeten JM et al from the Univ. of Washington in Seattle report of a study done in Kenya(2) with 318 HIV positive women to assess the relationship between selenium deficiency and HIV-1 shedding in the vaginal tract. HIV+ women can infect HIV negative men if HIV viruses are shed in the vaginal tract.
The study classified a deficiency of selenium as blood levels less than 85 mcg of selenium per liter. 11% of the women in the study were observed to have less than 85 mcg/l. The researchers found that selenium deficiency was associated with HIV-1 shedding in the vagina that was three-fold higher than women whose selenium blood levels were greater than 85 mcg/l. The implications are that, in sex without condoms, women deficient in selenium are 3 times more likely to pass the infection on to a man than women who are not deficient in selenium.
Hence, selenium supplementation may reduce HIV transmission in persons who not take other preventive measures such as using a condom. Note: A variation of this study that needs to be done is to determine if a selenium deficiency in men is associated with an increase in HIV in semen and sperm. The reverse of such a study is to determine if the level of selenium can be raised with supplements to 300 to 600 mcg per liter of blood, would this be sufficient to completely block HIV transmissin in both men and women?
If such an hypothesis could be tested and validated through studies, then perhaps selenium supplementation might someday become a condom in a pill in helping to prevent the spread of the virus that causes AIDS. Another area where the risk factor needs to be assessed by experts is this unanswered question: What is the risk of transmission of HIV from a person having unprotected sex with a HIV+ partner whose viral load is non-detectable (less than 50 copies)? Considering that nearly half the population has sex without condoms, these risk factors need to be assessed.
1. Look MP et al; Eur J Clin Nutr. 1997 Apr;51(4):266-72
2. Baeten JM et al; J Acquir Defic Syndr. 2001 Apr 1;26(4):360-4
3. Lancet, 2 (8291):175-9 1982 Jul 24
4. Am J Epidemiol, 122(2):276-82 1985 Aug
Cigarette smoking is one of the most commonly recognized drug addictions of our time. Being a two pack a day smoker for many years, I became aware, a long time ago, of the destructive effects of this compulsive habit. There is a long list of personal side effects that I will not enumerate. Very few people will quit smoking because someone badgers them into doing so. In fact, a nagging friend or relative will likely cause more anxiety resulting in a person smoking more.
I have found that when a person gets serious about quitting smoking, it will usually be for personal reasons and not because of fears of long term damage to ones health. It is when personal adverse effects take their toll that smokers get serious about quitting. By October of 1985, after 20 years of this addiction and feeling the side effects mount, I quit cold turkey, the most difficult experience of my life and one that I would not recommend again either for myself or anyone else.
I stayed off cigarettes until the spring of 1991 when a combination of stress and a roommate who smoked created an environment that enticed me into resuming the habit.
As the decade of the 90s passed by, the adverse effects slowly piled up again. Several New Years eve resolutions to quit came and went and were usually broken within the first 24 hours. The mounting side effects I experienced included nasty coughs and phlegm that sometimes came up in the morning too nasty to describe with the English language. There would be pains in the chest in various areas, increases in blood pressure, decreases in libido, not to say, the risk of lung and other forms of cancer, heart disease, the damaging effects on eyesight and the impaired sense of taste and smell.
Then there is the endless cleaning of windows, window shades, walls and woodwork as the tar and nicotine piled up, not to mention what the tar did to your teeth and gums. For the pleasure of the moment, I continued to poison myself, puff after puff and was unable to stop. I know the lure of cigarette smoking having done it for 30 years. I know that quitting cold turkey has a 99% failure rate and cemeteries are filled with the bodies of those who thought they could quit cold turkey and failed. I needed to quit again and to find a less stressful way of doing it. A gentler method than the cold turkey approach, that is very traumatic and often results in significant weight gain.
Besides personal adverse effects, smoking addiction lowers self esteem. Most persons who are habitual smokers think less of themselves because of their addiction. While the fear of weight gain often holds people back from trying to curb the addiction, the real reason for not quitting is lack of a realistic plan for successfully and painlessly with-drawing from the addiction.
In the past several years a number of observations about smoking addiction have come to my attention.
1. Cigarette addiction starts when smoke is inhaled into the lungs. People who never inhale cigarette smoke never become strongly addicted and usually can quit smoking with little effort.
2. Nicotine addiction is only part of the story, in fact, a lessor part of the story. The biggest part of the addiction is what I call SIA or Smoking Inhalation Addiction. There are substances in cigarette smoke that trigger pleasure centers in the brain. One substance, nicotine, is known, but there are one or more other substances that have not yet been identified. For this reason, smokers find it difficult to switch from smoking cigarettes to chewing tobacco, chewing nicotine gum or wearing a nicotine patch. A majority of people who chew nicotine gum or wear the patch will also smoke cigarettes at the same time. Cigarette smokers who puff on a cigar or pipe tobacco will often try to inhale the smoke. After they realize it is too strong to do this, they go back to cigarettes. Because of the addiction to smoke inhalation, it is rare to get a diehard cigarette smoker to switch to chewing tobacco, nicotine gum or the patch.
3. Stress, anxiety and depression are the factors that drive the addiction. Low serotonin and endorphin levels in the brain are major contributing factors to depression. A person who is asleep or in a state of total relaxation has no desire to smoke.
It is little wonder that an anti-depressant prescription drug called Zyban, has been effective in helping many people quit the addiction. However, Zyban does not work for everyone. I know of several people who said it did nothing for them.
In March, 2001, I decided to buy a Nicotine patch at a local pharmacy. Within 5 minutes of applying it, an itch so severe developed I was forced to pull it off. Then, it took several hours to get the spot where the patch was applied to quit itching. I decided that the tasteless Nicorette gum that had nicotine in it was my only over the counter option. Earlier, I had tried 2 different Smoking withdrawal homeopathic formulations from a health food store and found them too weak to work or have much effect at all.
The Nicorette gum helped. When I actually used the gum, I would stop smoking. The problem was the boredom of having a tasteless gum in your mouth all day. It wasnt long before I found myself smoking cigarettes again and the Nicorette gum would stay in the packet. The Nicorette gum did not satisfy me like the smoking did. I was still addicted, yet, I realized as I listened to my body and my lungs in particular, that they were hurting and telling me it was time to quit. Just how was this to be accomplished? I dreaded the thought of trying to do this cold turkey like I did in 1985 and the mental trauma this would cause. There must be a better way.
In April, I began pray daily and ask God for direction of how to break the addiction. This went on for several weeks. In May, I found a product, a Chinese herbal formulation called Tobacoff and bought a bottle of the herbs for $30.00. The instructions called for me to take 3 capsules 3 times a day until the craving for Tobacco ceased.
In May, I decided to try just one capsule to see how it agreed with my system and if any strange reactions would occur. None did, but within an hour I noticed the flavor of my next cigarette changed and that it tasted flat. The next day I took 2 capsules of the Tobacoff formula and found the flavor of the cigarettes would go flat and tasteless for about 2 to 3 hours. I then said to myself: if I am really serious about quitting, this herbal formulation will help as it takes the enjoyment out of smoking.
So for the next two months, I continued to smoke but by the 4th of July, 2001, I felt the time had come to get serious about finally ending the addiction. One morning I prayed again and asked for help. Almost immediately, the voice of God spoke silently in my mind and said: Look at your watch; take control of your addiction.
In an instant that followed a plan of action of how to break the addiction came into focus. Essentially, this was the plan, the plan that would finally work to end the addiction and would accomplish this with a minimum amount of stress and discomfort. It began with timing of the addiction and included the use of the Tobacoff herbal formulation and occasionally Nicorette gum.
Taking control of my addiction was the first step that enabled me to gradually reduce my dependency on cigarettes until I could finally let it go entirely. There are three factors that enabled me to do this They were:
1. The mind and free will - you must want to quit smoking as the most important immediate goal of your life. I was ready. I knew it was crunch time.
2. Find a place to keep the cigarettes other than on your person or in your home or place of work. Places to consider are the trunk of your car, basement, attic, locker, garage. etc.
3. When you do smoke, find a place other than your home or place of work. Suggestion: outside, porch, garage. Pick a place to smoke where you rarely spend much time. While quiting, keep the home and office a smoke free environment.
In July, 2001, I placed my cigarettes in the trunk of my car. This forced me to end my chain smoking habit. Anytime the cigarettes are on your physical person (ie shirt pocket), habit will keep up lighting up without realizing what you are doing.
Pick a date to start and mark your calendar. Try to avoid being around other people who smoke when you are quitting.
Days 1 to 3. For two pack a day smokers, smoke a cigarette once every half hour on the half hour when the minute hand reached 6 or 12 for the first 3 days.
Note: For one pack a day smokers, start directly with one cigarette every hour when the minute hand reaches 12 which is day 7 for the 2 pack a day smoker. O
n days 4 through 6, I stretched the time between cigarettes to one every 45 minutes smoking only when the minute hand of my watch reached 9, then 6, then 3, then 12. In a span of 3 hours, I would smoke 4 cigarettes.
On days 7 through 9, I stretched the time between cigarettes to one every hour when the minute hand reached 12 and at no other time. By the time I reached day 7, I had decreased my smoking from 40 cigarettes a day down to 16. Until day 7, I did not need the Nicorette gum or the Chinese herbal formulation called Tobacoff but now I realized that the cravings to smoke were increasing and something had to be done.
On day seven, I began to take the Tobacoff product using 2 capsules once every 4 hours. Once in a while between the hour span separating the cigarettes, I would take a bite or two out of a piece of Nicorette gum and them remove it from my mouth.
Almost immediately, the combination of the Tobacoff herbs and the occasional bite from the Nicorette gum took away the cravings almost completely. Three days passed and day 10 arrived. So far, the withdrawals had been easy and I remained in control of my addiction.
Days 10 through 12, I stretched the time between cigarettes from 1 hour to 1 hour and 30 minutes. Now this reduced my total cigarette use to 11 cigarettes a day. I continued to use the Tobacoff 2 capsules every 4 hours and occasionally chewed on the Nicorette gum.
On days 13 through 15, I further stretched the time between cigarettes from 1.5 hours to 2 hours. Now my consumption of cigarettes dropped to only 8 per day. I continued to use the Tobacoff and once of twice between cigarettes would bite on the Nicorette gum.
Days 16, 17 and 18, I reduced cigarette use to one every 3 hours and continued with the herbs and the Nicorette gum. By the time I got down to 5 cigarettes a day, I was ecstatic. I wasnt under stress, climbing the walls or grinding my teeth. It was really easy reaching this point. I began to feel like a prisoner about to be released. What a great feeling - to be free at last. Could I make the final stretch and finally quit and no longer have to think about cigarettes? Yes, I said to myself; I am going to win this race.
On day 19 and 20, I reduced the cigarettes to one every 4 hours, just 4 per day. By day 21, I knew That I could make it because I was already 90% to my goal.
On day 21 which fell on August 7th, 2001, I decided this was the day I would finally smoke my last cigarette. At 8 p.m. that night, I visited a friend who smoked regularly and told him this would be my last cigarette. In fact, it was the last cigarette I had in my pack. He said: If you want to quit, just quit, cold turkey. I told him that if you smoke over a pack a day, the cold turkey approach had about a 99% failure rate. I told him that quitting cold turkey now was not that much of a challenge as I was down to 4 cigarettes a day while a month ago it would have been impossible when I was smoking 40 cigarettes a day. I told him that my addiction was already 90% gone.
The advantages of gradual withdrawal: Little or no weight gain. Little or no stress. Increased self esteem with self control. The watch proved to be a valuable tool for taking control of the addiction and finally withdrawing from it.
Yes, it actually took about a month to quit. There were days when I smoked a few more cigarettes than I had planned. In fact when I smoked what I thought was my last cigarette at 8 p.m. on August 7th, it turned out not to be my last. On August 8th, a friend who smoked stopped over and I asked him for one cigarette and I smoked it at 10 p.m. that evening. On August 8th, I continued to use the Tobacoff herbs occasionally but no more Nicorette. I began to use a product called Smoking Withdrawal by Natra Bio for about one week.
I knew that of the two addictions, cigarette smoking and nicotine, that the smoking addiction was the strongest and the hardest to break, so once I stopped smoking, quitting the Nicorette gum was a breeze. One thing I also recommend to anyone quitting is to get plenty of chewing gum or peppermint candies. They help keep your mind distracted from the smoking addiction. Eating fresh fruit throughout the day is very helpful as this will keep your serotonin levels up to prevent depression.
The main thing is to avoid, at least for the first 2 weeks, spending much time around people who smoke or in public places where people smoke. The chemicals in second-hand smoke will awaken centers in your brain that will cause you to want to smoke. If you should take a puff off a cigarette, remember that the next morning when you wake up to think of yourself again as a non-smoker. People who take up the smoking habit after they quit do so for several reasons.
1. They live with or hang around with people who smoke or
2. Have depression, stress or anxiety in their life and/or
3. Have a self-image of themselves as a smoker.
Depression can be overcome by eating carbohydrates alone, without added fat. That is to eat fruit by itself or whole grain bread without butter. This will raise serotonin levels in the brain. Second, take a walk and drink good clean water. Walking and mild exercise (not weight lifting) increases endorphin levels. When your serotonin and endorphin levels are high, you are not depressed, you are cheerful and happy to be alive. Associate with people who have a positive outlook on life and avoid people who are angry, bitter, cold and negative. Watch a comedy on television or talk with friends whose sense of humor can make you laugh. Work hard, but play hard also.
Weight gain: By withdrawing slowly, appetite and weight gain are kept to a minimum. I gained 5 lbs after 3 months of being off cigarettes. By contrast, most people who quit cold turkey will gain about 10 lbs for each pack of cigarettes they were smoking when they quit. This is all the more reason to gradually taper off your addiction and thus prevent unwanted weight gain.
Note: Tobacoff is manufactured by Pacific Biologic in Clayton, CA. www.pacificbiologic.com or call 925-673-2967 to find out how to obtain the product. Tobacoff is the most important product I discovered to help a person quit smoking. It contains the Chinese herbs Yu Xing Cao, Shan Dou Gen, Yuan Zhi and red Ginseng. Cost is about $30 for a bottle. One bottle should be all you need. Nicorette gum can be found at any pharmacy and Smoking Withdrawal by Natra Bio can be found at most health food stores. Smoking Withdrawal is a homeopathic product and wont do you any good until you actually stop smoking. You may need it on occasion for about 2 weeks after you have had your last cigarette.
Painesville, Ohio: I had Lyme disease for 18 years before I received the proper diagnosis. For some time I used Venus Fly-Trap extract. It reduced the swelling in my glands by about 50% but I could not afford to stay on it. I decided to try vinegar. I have been on vinegar for 9 weeks now and the infections are better than they have been in the past 4 years. I use one tablespoon of Paul Braggs cider vinegar 3 times a day. I do not know if vinegar is gong to end up curing me, but so far, it has been a miracle. Thanks your so much for all your help. Susan Kramer, Painesville, OH 440-354-4384.
Spiro Kete: A product made by Kroeger Herb Co (Boulder, CO). Two out of three persons with Lyme disease who have used 2 capsules twice daily have reported relief from symptoms after 8 weeks. Spiro Kete contains Stinging Nettle, Yerba Santa, Goldenrod, Monolaurin and Organic Tobacco leaf. www.kroegerherb.com. Cost is less than $9.00 for 100 capsules.
Immax B and Immax A. Marah Cannon DC of Orange, CA has used IMMAX B in her Lyme patients who have autoimmune responses. She says the Immax B turns off the allergic reactions. After this happens, she switches them to Immax A for immune maintenance. She can be reached at 714-639-3935 for more information. Immax has been used successfully for treating allergies, asthma, arthritis and in higher doses 6 to 9 tablets daily for hepatitis C and for HIV infection. The sublingual tablets Immax A contains proteins of selected molecular weights to trigger immune cells to produce TH1 cytokines like IL2 and Il-12 while Immax B turn off excessive antibody production in the B cells. More information can be found at www.immunofoods.com.
Researchers in Kyoto, Japan at the Graduate School of Agriculture screened several fruits for their ability to induce Glutathione S-transferase and detoxify polycyclic aromatic hydrocarbons in a rat liver cell line. They found both papaya and avocado as significant sources of Glutathione S-transferase inducing ability. (1)
Note: Adding fresh avocado or papaya fruit to the daily diet may be an effective way to increase Glutathione availability and activity in the cells. Increased glutathione is known to improve antigen presentation and cell-mediated immune responses.
I have found that avocados imported to Wisconsin are usually green and hard. To ripen, place on a south facing window sill for a few days until they turn from green to a blackish color and the flesh soften when pressed. If you place a green avocado directly in the refrigerator, it will never ripen and will always be hard.
With Papaya, do not eat the seeds. They contain a powerful enzyme that can actually eat a hole in the lining of the intestines. Extracts of the seeds are used in hospitals to digest damaged spinal discs. The fruit is very safe to eat and very healthy also and contains a much lower level of enzymes that is not at the extreme level found in the seeds. Researchers have found that papaya fruit scavenges free radicals and the fresh fruit and leaves heals burns when applied topicly.
1. Nakamura Y et al, Cancer Lewtt 2000 sept 1;157(2):193-200
Jean Carper in her book FOOD - YOUR MIRACLE MEDICINE states the following about Avocados: Benefits arteries. Lowers cholesterol, dilates blood vessels. Its main fat, monosaturated oleic acid (also concentrated in olive oil) acts as an antioxidant to block artery destroying toxicity of bad-type LDL cholesterol. One of the richest sources of glutathione, a powerful antioxidant, shown to block thirty different carcinogens and to block proliferation of the AIDS virus in test tube experiments. According to Jean Carper, asparagus and watermelon also are high in glutathione. Persons dealing with chronic infections including HIV, HHV-6, candidiasis and cancer are all depleted in glutathione. These foods - fresh papaya, avocado, asparagus and watermelon could be very beneficial in supporting cell-mediated immune function in persons with these conditions.
Louise Tenney in her book Todays Herbal Health writes about avocado and states: Good for diabetic and hypoglycemic. Julia Lawless in her book on Aromatherapy states the following about avocado oil: Unrefined avocado aids dermal regeneration and is highly nutritious. It is recommended for dry, dull, dehydrated, aging skin and eczema. She recommends avocado for psoriasis also.
Take one ripe Avocado (you can ripen green avocados by placing them in a south facing window sill until the skin turns black in color and the flesh softens slightly when pressed) and place the green edible portion in a blender or food processor.
Add 3 tablespoon of lemon juice, 3 tablespoons of chopped onions, 1 fresh garlic clove, one fresh hot pepper (cayenne, jalepeno etc.), 2 tablespoons of Cilantro and 1/2 ripe tomato, a dash of black pepper and sea salt. Blend until smooth. Refrigerate and use within 3 days. This is the best tasting guacamole you will have ever eaten. Use it on baked potatoes in place of butter, on rye crisp and with baked organic corn chips. Use it as a dip for raw vegetables or as a spread on whole grain bread.
Watch your skin glow after using it for a week or so. Dry, aging, stiff skin is often a sign of glutathione deficiency and free radical activity. Avocados are also high in lauric acid. Try eating 1/2 avocado daily along with one serving of another glutathione rich food like cooked asparagus or a slice of ripe watermelon or papaya. Try to add raw foods in your diet to increase enzyme levels and further reduce stress on the immune system. Try to always eat some raw enzyme rich foods with each meal of cooked foods. Good digestive aids besides papaya are raw ripe pineapple and kiwi fruit.
Wayne Martin writes an interesting article on Heart Disease and Cancer in the April, 2001, issue of the Townsend Letter for Doctors. He reports on research that shows that the polyunsaturated vegetable oils have been used to prevent rejection in renal transplants and another reference for treating multiple sclerosis, thought to be an autoimmune disease. Martin cites the research of Dr. R.A. Newsholme of Oxford University on Mechanism for Starvation Suppression and Refeeding Activation of Infection. Quoting Newsholme, Martin states: in the absence of starvation, we get in our diet immunosuppressive polyunsaturated fatty acids, and hence are prone to having bacterial and viral infections. When we starve, our body store of polyunsaturated fats is depleted and then our immune system activates and will tend to abolish an existing infection while preventing other infections.
Martin quotes from Oncology Times in January, 1982, that mice fed polyunsaturated fats were more prone to develop melanoma and in 1980 the same publication reported that polyunsaturated fats fed to cancer prone mice increased the number of cancers formed. Wayne Martin, Fairhope, AL 334-928-3975. For some time, I have been warning about the use of nearly all the refined vegetable oils currently sold on the market. They are contributing to both cancer, heart disease and now immune suppression. The dangerous effects occur when high heat is used in processing these oils altering their molecular structure and turning these oils into toxins. BEWARE OF ALL PROCESSED FOODS.
An article by Susanna Cunninghan-Rundles and 10 other researchers at Cornell Medical Center in New York City titled Probiotics and Immune Response was published in the Am J. of Gastroenterology (1) in January, 2000. The research was done to determine if giving children born with HIV the probiotic L. Plantarum orally would improve nutrient status and promote growth. The researchers stated that some probiotics produce nutrients, absorbable peptides and vitamins essential for the host. The colonization of the intestines with friendly bacteria may prevent overgrowth of the unfriendly bacteria.
The first child to be tested with oral use of L Plantarum was 11 years of age and had candidal esophagitis and chronic diarrhea. He was given L Plantarum (299v) for one month. After one month of treatment, his mouth ulcers, candidiasis, and diarrhea resolved. The childs appetite improved markedly, he ate three full meals a day and he was able to enjoy playing again. The improvement in weight was statistically significant." As a result of this one case a double-blind controlled study was undertaken involving 17 children to test the effects of the oral administration of L Plantarum.
Rundles et al state that no child was withdrawn from the study because of side effects or problems with taste. Colonization is reported to have taken place in 2 weeks. The amount of L Plantarum taken was not stated in the article.
Of 17 children studied, the researchers stated that 10 were responsive and 7 were non-responsive. Responsive meaning that positive results were noted. No information in the article was given as to the diet of the children, any medicines they may have been taking and no mention of whether any prebiotics (fiber and non-digestible carbohydrates) were taken.
Interestingly, the article states that a child with marked growth failure born to an HIV positive mother, was subsequently found to be HIV negative by PCR and eventually showed seroconversion of the previously positive HIV antibody reactivity. Of this child they also observed gains in height and weight and a marked augmentation in immune response. They further added: This difference reflected a change from generalized anergy to normal immune response within 1 month and occurred in the absence of any other intervention or treatment.
The authors reported on other studies that showed that lactobacillus improved phagocytic activity in peripheral blood cells. Phagocytic means the ability of certain white blood cells to engulf and destroy bacteria and viruses in the blood. The authors concluded that L Plantarum has the potential to improve growth, development and immune response in HIV+ children.
The authors did not claim that one of the 17 children in the study was cured of HIV infection although they reported in the absence of any other treatment, the blood levels of HIV by PCR were non-detectable and the HIV antibody status that was positive became non-reactive or negative.
The big question for us is whether these kinds of results can be duplicated. Unknown and not mentioned is whether the HIV antibody status of this child will remain negative if the use oral use of L Plantarum is discontinued. Other researchers report that L Plantarum produces a two peptide antibiotic that they call a lantibiotic. (2) Researchers at the University of Washington in Seattle, WA, report that Vaginal colonization with lactobacilli should be evaluated as potential interventions to reduce a womans risk of acquiring HIV-1, gonorrhea and trichomoniasis. (3)
1. Am J Gastroenterology 2000 Jan;95(1 Suppl):S22-5
2. Microbiology, 2001 Mar;147(Pt 3):643-51
3. J Infect Dis 1999 Dec; 180(6):1863-8
The following exchange took place on May 30, 2001
Mark: You left a phone message with me the other day that after 14 years of being HIV+ and only using prescription drugs once for 2 months several years ago, that your CD4 count is 524 and your viral load is 8000. When was this test taken?
Tracy: Last week of April (2001). It had been 5 years since my last lab test.
Mark: Sounds like you dont like to see a doctor very often.
Tracy: Thats right. I have never been sick with any opportunistic infection in the past 14 years. Ive had two ex-lovers die of AIDS and I have buried 75 friends from this disease. Since 1987, Ive only used the prescription drugs for HIV for 2 months and that was 5 years ago.
Mark: The trauma of living and dying from AIDS has hit the gay community very hard since the mid 1980s. In the past few years, a great portion of society has reached a stage of mental burn-out on this subject. Today, an increasing number of married (heterosexual) women are becoming HIV+ and are contacting us for help. In the US, it is harder for heterosexuals to deal with HIV than gays, especially when it comes to peer support. This is because of the myth that only gays, bisexuals, drug addicts and prostitutes get the disease. Worldwide, the majority of persons infected are heterosexuals (especially in Africa and Asia). This virus follows the Armys dont ask, dont tell policy. It doesnt ask our sexual preference, it just infects anyone when the opportunity is provided. Tell me something, in the past 14 years, when was your viral load the highest and your CD4 count the lowest?
Tracy: That was about 5 years ago. I had a lab test that showed my viral load at 50,000 and my CD4 count had dropped to just under 300. The doctor told me that I needed to start on the drugs immediately or I would die. So I relented and started on Zerit and Epivir. I took it for two months and it made me real sick so I quit.
Mark: Most of our readers tolerate these two drugs very well but people react differently. What did you do then?
Tracy: I took lots of herbs.
Mark: What kind of herbs?
Tracy. Well, let me take you back to the first year, 1987. For about one year, I took oral hydrogen peroxide, 35% food grade quality solution. I used 10 drops in a glass of water twice a day. I did this for about one year and then stopped. Then I took Essiac tea for several years and also took acemannan. In fact, I still use Essiac tea from time to time, but not on a regular basis. [Note: Essiac is the herbal tea discovered by the Ojibwa Indians in Canada that has been used for treating cancer for the past 80 years.]
Mark: What is your current protocol?
Tracy: For the past 5 or 6 years, I have done the following: Aloemannan (Royal Body Care) 3 caps 2X Colostrum (Royal body Care) 3 caps 2X Spirulina (Royal Body Care) 3 caps 2X Maximizer Enzymes (R-Garden) 3 caps 2X Inner Garden Flora (R Garden) 3 caps 2X For the past year Ive taken 2 capsules daily of MSM. I also take a multiple vitamin formula from Sunrider. Once every two weeks for 3 days I take Colloidal silver 500 ppm) - 1 teaspoon in a pint of water each day for 3 days, then I stop.
Mark: What kind of diet are you on?
Tracy: Average. It could be a lot better. I have eggs, bacon and toast for breakfast, nothing for lunch and for supper I eat a regular meal of meat, potatoes, a salad and vegetables. I also eat lots of fruit.
Mark: About your intestinal health, do your stools float on water?
Tracy: Always, at least for the past 5 or 6 years.
Mark: Interesting. About 10 years ago we discovered that persons HIV+ who consistently had floaters were non-progressors. In the last few years we learned that stools that floated on water was directly linked to the amount of friendly flora in their intestines. Also, we found that persons with CFIDS, Lyme disease, hepatitis, cancer, candidiasis and multiple food allergies had stools that would sink in water, just like most persons with AIDS do. This correlation was true in about 90 to 95% of the anecdotal cases reported but surprisingly not 100%. By the way what kinds of flora are in RGarden?
Tracy: Ill read it off the label. It has L. Acidophilus, B. Bifidum, B Longum, L Plantarum and L. Salivarius.
Mark: What an interesting coincidence. These are the same five strains that we have found to be most important for intestinal health. Where did you learn about R Garden?
Tracy: It was in your publication several years ago.
Mark: I do recall writing about it. It must have been 6 or 7 years ago. Too bad we let this one get away from us. What is encouraging is that you have had such incredible results for the past 5 years with your protocol and it would be unfair to give all the credit to R Garden. We have had other isolated and good reports on the Ojibwa tea and the vegetarian digestive enzymes as well. Thank you for sharing your experiences with us. Persons who want to contact Tracy can send an email to- email@example.com
In the heart of Nairobis worst slums, Sister (Didi) Rucira opened, in July 2000, the first homeopathic clinic in Kenya to treat persons living with AIDS. The ABHA LIGHT HEALTH CENTRE uses homeopathy as the main treatment but will apply any natural treatment that is affordable. In an email message to me, Didi (means Sister) Rucira requested a copy of our book on reversing immune dysfunction. We have mailed her 2 copies, one for the clinic and one for her classes on healing and health services that she offers in Kenya.
Didi writes on her web site that official statistics says that one in every 8 persons in Kenya is infected with HIV, but at her clinic, she reports that 40% of her clients have HIV. Didi reports that the decimation of the family structure is spreading at an alarming rate as one or both of the parents die of AIDS. She says that AIDS is ostracized here and that if a family member is known to have the disease, they are thrown out and are also rejected by their own friends and community. Even children are thrown out of homes if they are thought to have HIV. Didi states: It is beyond comprehension what Africa will look like in 5 or 10 years time.
To complicate matters, hospitals, clinics, doctors and nurses, do not tell the patients of their HIV diagnosis even when they know it and the patients are not told what they are being treated for. Didi: I see many HIV+ patients, but its never about HIV. Its always: Ive got a cough, a headache and a belly ache. Ive got diarrhea, dont have any appetite and Im losing weight. HIV is never mentioned. Then there is PCP and Tuberculosis that Didi describes as a painful, dry, hacking cough with bloody expectoration.
Her clinic treats several hundred patients each week and a mobile health service that reaches rural areas has given health services to thousands of afflicted persons. On her web site, she is asking for volunteers to come and work at her clinic and well as donations to support it. The website is http://home.pacific.net.sg/~rucira/alf. The address to write or send donations is Abha Light Health, PO Box 6919. Nairobi, Kenya. A link to her web site has been placed on our home page at www.keephope.net.
There are 8 homeopathic remedies that Didi refers to as the big 8 on her web site that she gives all her AIDS clients for starters. They are phosphorus, arsenicum alb, pulsatilla, mercurius sol, thuja, medorrinum, lycopodium and silcea. She also uses a lot of herbal tinctures, alfalfa and echinacea. She gives the big 8 for persons with HIV on the first visit as there are so many people and so limited resources to diagnosis and recommend more specific treatments.
One volunteer, Tim describes a typical day at her clinic: waking up around 6:30 am, taking a bucket bath (there is only electricity starting from about 11 pm till 6:30 am), packing up our medical equipment, medical books, laptop and lunch and getting into a taxi to take us to the slums. We arrive at 9 am at the clinic, and are besieged with patients of every variety till about 5 or 6 pm. We leave on a matatus which are minivans packed with passengers which costs about 10 cents for a ride. The ride is incredible as there are no rules. There are no stop signs or traffic lights, so drivers simply vie for right of way randomly, it is incredible chaos. Drivers routinely go up on sidewalks and over top of everything. There is virtually no pedestrian right of way. Once we arrive home, we eat some fruit or whatever Didi has prepared, usually delicious and nutritious. Then we get to solving the cases of the day which usually takes many hours. Then we go to sleep and the next day start all over again. We have Fridays off, teach all day Saturday, and 3 hours on Sunday. Over all, Tish and I feel so privileged to be here. The people are beautiful, the children are so free and wonderfully alive. It is also exciting to see some of these wonderful cases. Warmly, Tim.
Finding particular articles in past issues of Positive Health News on our web site became easier on July 1st, when I added a paragraph under each issue describing the title of most of the articles published in issues of Positive Health News published since 1995. The summary was made possible thanks to the help of Eusibo, one of our readers who helped prepare the table of contents. The summary of the contents comes up when Positive Health News is double clicked on the home page. When printed out, this 3 page summary gives your an overview of some of the most important articles published in the last 5 years and makes locating the information a whole lot easier.
Research published as long ago as 1990 at Brandeis University in Waltham, MA, discovered that dietary palmitic acid found in Palm oil increases the good HDL cholesterol and reduces excess levels of LDL (1). Researchers Lindsey, Benattar , Pronczuk and Hayes stated:
Replacing 12:0 plus 14:0 from coconut oil with 16:0 as palm oil induced a significant increase in high density lipoprotein (HDL) with a trend toward decreased LDL. Note: 16:0 is Palmitic acid whereas 14:0 is Myristic acid and 12:0 is lauric acid.
HDL, known as High Density Lipoproteins are responsible for keeping LDL (Low Density Lipoproteins) in solution and preventing them from depositing on artery walls. In fact, HDL counts below 35 are considered to place a patient at risk for developing CVD (Cardio -Vascular Disease). The ratio of LDL to HDL or LDL/HDL should be 4 or less. The ratio is determined by dividing the total HDL into the LDLs. The higher the resulting number is above 4, the greater the risk of developing CVD. In other words, if the LDL is 160, the HDL should be 40 or higher.
Researchers have found that vegetable oils high in polyunsaturated fats (PUFAs) decrease LDL cholesterol which is good but also decrease the HDL cholesterol which is bad (2). The vegetable oils high in PUFAs are commonly found in grocery stores and include corn oil canola oil, sunflower oil and others.
Researchers at the University of Montpellier have found that Crude Palm Oil used in conjunction with fish oil produced a better lipid profile in rats to prevent CVD than fish oil used in conjunction with refined Palm oil. They found the HDL/LDL ratio to improve, lower triglycerides, and apoB and apoA1 to be depressed and enhanced, respectively (3)
Other than Palm oil and fish oil , researchers have found that olive oil promotes a good lipid profile. In Venezuela, researchers found, in animal experiments, trying various combinations of fats that platelet aggregability was lower in animals fed with palmitic acid rich diet. (4) Platelet aggregation or blood stickiness is responsible for strokes and blood clots in CVD. Several other products have been found to stop blood cells from sticking together ranging from Aspirin to cayenne to cider vinegar to some antioxidants like Pycnogenol and olive leaf extract. In Spain, researchers found in humans that after a diet high in Palm oil called Palmolein, that lipid peroxide value were lower than those for sunflower oil. (5)
Research done is Africa of two groups of rats, one fed fresh Palm oil and the other fed oxidized Palm oil. Both oils increased the HDLs but the oxidized oil increased the blood pressure and also higher LDL levels than the fresh Palm oil. (6)
A new margarine has reached grocery shelves in the United States that uses current guidelines from the American Heart Assn. for lipid blends and is not hydrogenated and has no trans fatty acids. The AHA has found that the best lipid profiles in the blood to prevent CVD come from using 1 part Saturated oils, 1 part Mono-unsaturated fats and 1 part Polyunsaturated fats. Smart Balance is made by Heart Beat Foods in Cresskill, NJ 201-568-9300. This is the first good tasting margarine on the market that contains no trans fatty acids and may help prevent CVD.
On his website, Paul Newman www.newmansownorgaincis.com, reports that Palm oil that comes from the fruit should not be confused with Palm Kernel oil that comes from a nut. The present research support the use of Palm oil, not Palm Kernel oil.
A possible good combination is to use Palm oil and Olive oil together. To decrease the lipid peroxides even further, take olive leaf extract capsules with 20% oleuropein. Two to four capsules daily have reduced the LDL cholesterol and along with Palm oil and Olive oil should improve the HDL/LDL ratio and lower the free radical lipid peroxides. Salmon, Sardine and Cod Liver oil high in DHA/EPA also significantly improve the HDL/LDL ratio and lipid profiles. Elevated homocysteine levels have also been linked to CVD. B12 and Folic acid are known to lower homocysteine levels.
Note: For several years, I have looked at lab results of persons doing poorly (with HIV, CFIDS etc.) and have always observed a low level of HDLs. Low HDLs may be linked to a failure of cell-mediated immunity and improving the HDL/LDL ratio might also improve immune function.
1. Proc Soc Exp Biol Med 1990 Nov;195(2):261-9
2. Br J Nutr 2000 Feb;83(2):151-9
3. Int J Vitam Nutr Res 1999 sep;69(5):330-6
4. Scorza et al. Arch Latinoam Nutr 1999 Mar;49(1):20
5.Eur J Clin Nutr 1998 Sep; 52(9):675-83
6. Afr J Med Sci 1996 Dec; 25(4):335-40
Since the Spring issue of Positive Health News and the article I wrote on immunizing chickens to produce immunized eggs to treat HIV and other infectious diseases, I have been waiting to hear from someone who actually would carry out this experiment. The email from Jose who lives near Sao Paulo, Brazil, was most welcome news when it arrived on July 15th. Here are some excerpts from his letter:
This is the first report on my experiment with Hyper immunized chickens eggs in Sao Paulo, Brazil. On June 16th, I purchased 10 hens from a large chicken farm. The chickens had been kept in individual cages. I placed them in large chicken houses with 5 square meters of lawn so they get in contact with the soil and resume their chickens habits. I let them adapt to their new environment for 13 days and fed them organic grains, natural minerals and vegetables.
On June 29th, I drew some of my own blood and injected subcutaneously 2 or 3 drops or about .2 ML under the skin in the thigh area of each of the 5 chickens. The syringe I used was a 1 ML, that is used for insulin injections. Since the inoculation, the chickens have continued to lay eggs every day.
On July 7th, I did a second immunization in the same five chickens with about the same amount of blood. This time, I had a friendly nurse draw 10 ml of my blood in a vacuum tube.
The eggs from July 9th gave a very strong reaction. I eat one egg daily. The effects were a low grade fever, sore throat, running nose and body aches (flu-like symptoms). I add the egg to some cold milk plus a little honey and whip it in a blender. After a few days of using the immunized eggs, the only symptom that remained was a sore throat after eating the raw egg."
Jose ----- email: firstname.lastname@example.org
On Monday, July 16th, I called Jose and we had a brief discussion:
Mark: I was very happy to receive your email and glad to see that someone has actually taken a concept beyond the idea and discussion stage and acted upon it.
Jose: I have read your publications for a long time and admire your tireless efforts. I am very excited and hopeful about this experiment.
Mark: That makes two of us who are optimists. Has your energy level been affected by the immunized eggs?
Jose: Yes, I would always wake up feeling like I have a hang over and then there is fatigue that lingers all day. I can say that for the past week I dont feel this any more. I wake up without the hang-over feeling and I have more energy.
Note: In our conversation, I suggested that he eat two eggs daily instead of one. He began doing this on July 17th.
On July 25th, I received an email from Jose who reported on his first lab result since eating the immunized eggs. He reported his platelet counts have increased from 113,000 to 153,000. He wrote that the increase is a more marked one. He added: I intend to run a PCR for HCV tomorrow. I just cant stand it. I will let you know as soon as any results become available.
Note: Jose told me that the nurse that drew 10 ml of blood for the second inoculation of the chickens added some anti-coagulant to the blood. I have reservations about adding an anticoagulant to the blood as one anticoagulant, heparin is reported to inactivate lipid enveloped viruses. Blood drawn at room temperature usually remains a liquid for a few days. If the person drawing the blood feels an anti-coagulant is needed, it would be better to add an equal amount of distilled water.
In our discussions, Jose talked about doing an IM (intramuscular) injection of his blood or using larger amounts in a third inoculation of the chickens. I advised him against using more blood or an IM injection. I reasoned that too much blood could cause excess stress on the immune system of the chickens and possibly do permanent damage to its immune system as the blood cells will battle each other. Doing the injection subcutaneously is done to prevent the human blood cells from getting into the animals veins and arteries. What we want is to get the viruses and other infectious agents into the capillaries of the chicken and not foreign blood cells. In my opinion, a single drop of blood is all that is needed to inoculate a chicken or a goat. With a chicken, you could add up to 1/2 cc of distilled water to one drop of blood and with a goat 2 drops of blood to one cc of water.
Note: Jose has offered to immunize his other five chickens for anyone in Brazil with HIV, hepatitis or any other chronic infection to produce their own personal hyper-immunized eggs. You may contact him be email at email@example.com
Note: Robert Carson MD, told me that adding distilled water to blood would lead to a breakdown of the blood cell walls and a release of viral particles into the blood serum. He concurred with the theory that adding distilled water to a few drops of blood might increase the inoculations effectivenss as more viral particles are released from the infected cells. This turned out be be the method that Barbara used on July 25th.
United States: somewhere on the East coast. Last month I reported a planned immunization of a goat with HIV-infected blood from one of our readers. Barbara was diagnosed with AIDS about 5 years ago in 1996. Before immunizing her goat, she had blood drawn for lab tests on July 23rd. Her numbers were sobering. CD4 count was 21 and her viral load for HIV was listed in excess of 500,000. This is because the test used only measures up to a 500,000 viral load.
Last month, Barbara, who lives on 2 and 1/2 acres with her 5 children, had planned to infuse her blood in the hind teat of the goat using a syringe with an attached Teat Infusion Cannula. On Wednesday, July 25th, at 9 am, she pricked her finger and drew out about 6 drops of blood that she added to 1/2 teaspoon of distilled water. I had suggested to her a few days previous that if she could not get enough blood by pricking her finger to just add it to a small amount of distilled water.
She drew the blood and water mixture into a 3 CC needle syringe. Then she placed the Cannula over the needle and inserted the Cannula into one of the hind teats of the goat. As she began pressing on the syringe plunger, the blood and water mixture started comming out of the bottom of the Cannula instead of going into the udder.
Seeing that this method was not working, she withdrew the syringe and Cannula from the udder and looked for an area of loose skin on the goat to inject the animal subcutaneously. She found a spot on the left side, midsection near the belly that had some loose skin. She inserted the needle at an angle and injected the blood and water mixture under the skin. Immediately, the goat began to dance and stomp around thinking it had been bit. She injected the full 3 cc that was in the syringe.
After the inoculation was over, she noticed that the needle was removable from the syringe and that the Cannula fit over a tube that the needle had occupied. Never having used a Cannula before is why the teat infusion attempt failed. Never-the-less, with the subcutaneous injection, the goat was now exposed to the HIV in her blood and events would soon take their course. She called me shortly after doing the immunization of the goat to tell me what had transpired.
I told her that for now all we could do is wait for a sign that the goat was fighting an infection. The sign we were waiting for was for the goat to develop a fever. I told Barbara that there would not be any immune modulating value to the milk until this happened. I said: with the chickens in Brazil, it took 7 to 10 days before the eggs started producing immune reactions, so I wouldnt expect anything to happen too soon.
On Thursday morning, July 26th, Barbara called to tell me that by 7pm Wednesday evening, just 10 hours after the inoculation, the goat was showing signs of being heated and was feeling hot. She said: the goat had a major fever last night.
My first reaction was one of surprise. I had expected a reaction from the goat, but not this soon, and not on the same day of the inoculation. I inquired as to how the goat was doing this morning. She said the goat was not as lively as it usually is. It is eating less and acting tired. After we got off the phone, Barbara drank her first cup of milk that she had obtained from the goat on Wednesday evening at the same time the goat was breaking with a fever.
Later that day, only a few hours after drinking the first glass of immunized mik, she called to report that she too had developed a low grade fever. It was Thursday evening and this story was just beginning to unfold. For the next several days, she would drink one cup of goats milk in the morning, the milk have been drawn on the previous day. With strong reactions setting in, there was no need to up the dosage.
On Friday morning, I called Barb to see how she was doing and she reported that she had developed night sweats last night and had not had these in years. She had a headache, her nose was running, her muscles were aching and her throat was sore. She said her temp was just over 100° F. I told her that these were flu-like symptoms and a sign of strong immune activation and that her symptoms were similar to Joses in Brazil, except hers were much more intense.
She continued to drink one cup of the goats milk each morning from the previous days milking and all the symptoms persisted but slightly less intense on Saturday evening and Sunday evening. On Sunday, she reported that her urine turned brown in color and emitted a very strong odor.
By Monday morning, the headaches stopped and the aching muscles were gone and the color of the urine had returned to normal - clear and slightly yellow. By Tuesday morning, her appetite was returning and she began eating normally. However, a few hours after her morning drink of the goats milk, a low grade fever will develop. By late evening each day, the temperature will reach 101 or 102° F. When it reaches 102, she takes a Tylenol and it drops about 1 degree. On Thursday, August 2nd, the night sweats stopped.
This morning, August 3rd, the 9th day into this experiment, Barbara reports that the only symptom remaining is the fevers that are most noticeable in the evening. In the morning, her temperature is either normal or just slightly elevated. She continues to eat normally and has no more headaches, night sweats or aching muscles.
Sunday, August 5th. A phone call found Barb not feeling well. Concerned that she might be overdosing on the immunized milk, I suggested she stop using the goats milk for a few days and to resume at a reduced dose when she feels back on track. Barb has also been taking Diflucan for a yeast infection. It is not also beyond the range of possibilities that she may be developing an allergy to the goats milk or there still could be yeast overgrowth or die-off causing her to feel not well. I suggested she get a new diagnosis from her physician to determine if other factors have been overlooked.
Houston, TX, July 13, 2001: A reader (Patrick) called and reported that for the past five month his skin has been covered by small red dots and the doctor said it was a fungal infection. He had this condition for the past 5 or 6 months. Prior to January, the patient has been using Norvir, 2 capsules 3 times daily along with Zerit and Epivir. On this protocol, he experienced no side effects and his viral load was non-detectable and his CD4 counts were normal. In January, for no apparent reason, his doctor said: Lets try Ziagen (Abacavir) and Combivir (AZT and 3TC), two products made by GlaxoSmithKline. By the end of February, a rash developed and not even a months worth of antibiotics could budge it nor could any treatments offered by the dermatologist nor did a home made garlic oil ointment with coconut and oil olive oil help. In addition the patient developed insomnia.
My opinion was that the patient might have an excess of histamines causing the red skin condition. Since the condition developed after he started on the new drug cocktail, I suggested he go back to the cocktail of Norvir, Zerit and Epivir he used last year before this condition developed. I have very high regards for this combination.
For some time I have heard that physicians are offered bonus checks by some pharmaceutical companies for meeting prescription quotas for certain drugs. Was a bonus check a factor in the physicians decision to change the patients protocol? The patient had been doing very well on Norvir, Zerit and Epivir. His viral load was non-detectable. His T cells were normal and he had no side effects. So why did the physician make the change? Was it to get a bonus check? These unethical practices need more exposure. Physicians should give prescriptions to patients based on what is most beneficial to the patients and not their pocket book. I have heard about these promised bonus checks from various sources and some practicing or retired physician needs to come forward and spill the beans on these unethical practices.
Hello Mark, Im writing first to say thank you for such a helpful and inspirational site. Ive used the whole lemon/olive oil drink on and off for several years now with great success, normal liver function being one, despite the heaviest drug regime.
For the past 3 years I have been taking liquid zinc, magnesium and selenium (http://www.immunova.bm/) with amazing results (instant genital herpes healing with no recurring outbreaks, increased energy, libido, sense of well-being, increased CD4 counts etc.) from a scientist I befriended at a clinic here in London.
This past May (2001), I added Moducare, 2 tablets 3 times a day which I feel has stopped my anxiety and given me a feeling of calm like nothing I experienced before. My MAI/MAC infection of neck and abdominal lymph finally cleared within two months after two years on antibiotics. Had no improvement prior to taking Moducare.
Previously to 1999, I suffered from KS cancer pretty much all over my body. On the advice of a friend who had total remission of his KS from Maitake tablets (7 X 3 a day) I took the plunge and started the Maitake, with a CD4 count of 17 and after 3 months on the tablets, my KS stopped and faded. No one was more surprised than me. I say this because I have NO faith in any type of medicine/remedy/herbs etc. My feeling is that this stuff has to prove itself to me. This same friend lent me your manual on How to Reverse Immune Dysfunction.
I would love to hear from anyone using Moducare, Maitake or liquid zinc. Simon ....... firstname.lastname@example.org or email@example.com
Chicago, IL: One reader on a drug cocktail (Crixivan, Zerit and Epivir) for HIV took 2 TF+ (4-Life Products) capsules daily for 6 days prior to his latest lab test resulting in a doubling of his CD4 counts from 219 to 434. This was his first use of TF+. He credits the TF+ for the sudden increase in the CD4s since he had been on the same drug cocktail for several months with no upward movement in the CD4s although his viral load was non-detectable.
Meanwhile, Gary B, one of 6 HIV+ persons using 2 capsules daily of TF+ and a combination of Viramune, Zerit and Epivir, who had reported earlier increases in his CD4s, reported a small decrease in his CD4s in the 4th month of using the product although his viral load remains non-detectable. Update: By the 6th month, Gary now reports new gains in the CD4 count that are now at their highest level in 7 years.
Note: Transfer Factor Plus by 4-Life Products appears to work synergistically with a drug combination cocktail to reduce viral load or increase T cells counts . As a stand alone therapy, 2 capsules daily do neither.
CFIDS: Jim who has CFIDS and lives in Florida reports significant benefits and relief from most of his symptoms from using TF+ in high doses (up to 10 capsules daily). (Jim 561-805-5787)
Both Norvir and Kaletra are protease inhibitors made by Abbot Labs. Kaletra, a recent drug, is a lower dose version of Norvir with a supposedly improved delivery system. However, we have had two readers who used Kaletra in combination with other drugs for treating HIV and both said that Kaletra did not work. Their viral loads have increased significantly. Norvir is still available and has a history of remitting KS lesions, cancers and strongly promotes antigen presentation and DTH responses, indicative of strong cell mediated immune reactions.
In our opinion, we are not convinced that Kaletra is an improvement over Norvir and Norvir remains our number one choice as an FDA approved immune modulator and anti-viral for treating AIDS. Norvir works well in combination with Zerit and Epivir. Norvir works with fewer side effects if used three times daily in smaller doses instead of twice daily in the standard dose of 6 caps 2X as originally recommended by Abbot Labs - a dose too high to be tolerated by most persons.
For dosing, we suggest dividing the total body weight in pounds by 20 to equal the total number of capsules to use daily and then divide this into 3 portions. Example: 180 lbs divided by 20 = 9 capsules. This equates to 3 capsules taken 3 times daily.
Sao Paulo, Brazil: Aug. 24th: After using the immunized eggs for about 17 days in July, the PCR results of July 26th that arrived on August 24th showed a decline from last years level of 200,000. Jose writes:
My PCR test results (from July 26th, 2001) was 150,000 for the HCV. That is a log 5 but close to log 4. I used to have log 6 or 1.5 million. I probably did not give enough time for the immunized eggs to work properly. I shall try again later. I am happy with the results however. Jose.
Reader reports increase in CD8s along with weight gain but no decline in viral load USA: Update on Barbara who we reported immunized her goat on July 25th, 2001. On August 14th, she immunized the goat again subcutaneously with 6 drops of blood in 3 cc of distilled water. The fevers and night sweats that started on July 26th have lasted the whole month of August along with severe fatigue.
On August 27th, she had blood tests done for T cell counts and viral load for HIV. The results were disappointing when the viral load remained above 500,000. Both PCR tests had this limitation as neither the baseline test or the August 27th test could measure viral loads above 500,000. The CD4s decreased from 21 to 13 while the CD8s increased from 183 to 324. The red blood cell count was low and the hemoglobin levels were subnormal.
In spite of this disappointing news, Barbara reported a gain of 8 pounds since the last week of July. At my urging, she decided to ask her physician for a prescription of Viramune, Zerit and Epivir, a non-protease combo that a number of readers have had very good results with. She is expected to start on the drug combo sometime in the week of September 10th.
Meanwhile, she said the goat has been impregnated and will have a kid in January or February next year. She plans to keep some of the Colostrum for herself. The Colostrum is thought to have the highest concentration of immunoglobulins, transfer factor and other immune factors.
Note: Last month I had serious doubts about Barbara doing this experiment when her CD4 count came back so low (21) and her viral load was so high (over 500,000). I felt that the experiment would stand a better chance of success if the CD4 count was 200 or higher. In spite of the disappointing lab results, Barbara indicated no regrets in pursuing this experiment and is looking forward to using the Colostrum next year.
Update: Sept. 14th: Barbara reports that on 9/13, her physician drew blood for yet a third set of lab tests for viral load and T cell counts. Barbara reports that although she has stopped drinking the immunized goats milk for the past two weeks, she is still getting the daily fevers and night sweats. The new lab results will be known in the 3rd week of Sept., just before starting on the anti-HIV prescription drugs. She has been very reluctant to start on the meds but knows this is what she must do, at least for now. I suggested she also start eating foods rich in selenium.
Update: October 31st: Barbara has been on Sustiva, Zerit and Epivir for the past month along with antibiotics to treat a MAC infection. Her latest viral load dropped from over 500,000 to 9900 and her CD4 count increased from 15 to 65. She has not consumed any goats milk since the end of August but told me today, she plans to resume drinking the milk. For now, her prospects for survival look very promising. While the immunized goats milk increased her CD8 counts in August, it was not sufficient to bring down her viral load or increase her T cell counts. Possibly, if the experiment had been done several years earlier when her immune system was more intact, the results might have been more promising.
Until the fat lady sings, nothing I have written here at Keep Hope Alive is set in stone. Our ongoing efforts to develop a low-tech oral vaccine or personal transfer factor are both a learning experience and evolving process. Not every idea we try is going to work and a number of failures can be expected. An idea proposed last month can easily be replaced with a better one this month and so on it goes. What is ultimately important is that a sound idea emerges one day that works very effectively and constitutes a significant breakthrough in the ongoing war against chronic infectious disease.
In the evolving methods of immunizing chickens and goats, there are reasons for suggesting an infusion in the colon of the chicken or in the case of a goat in the udder might be an improvement over a subcutaneous injection.
First, a rectal or mammary implant eliminates the risk of human blood entering the blood vessels of the animal which could cause unnecessary stress to the immune system of the chicken or goat and second, because this risk is eliminated, you can increase the amount of blood from one or 2 drops to 20 drops or more and increase the viral exposure significantly to produce a more potent immunized egg or milk. Third, the membranes of the intestines of the chicken or goat will act like a fine filter to keep out the human blood cells, thus preventing the chicken from producing antibodies against human blood cells. At the same time, the intestines allows the viruses and other pathogens to penetrate the intestinal walls and to expose themselves to immune cells in the intestines.
The Herb Saunders method of mammary infusion while the mammal is pregnant has had 20 years of experience behind it. However, as chickens do not have udders (mammary glands) a colonic infusion is the logical alternative. A syringe with a Cannula sleeve can be used to give either a colonic or mammary gland infusion in either a chicken or a goat. In a goat, two intermammary gland (udder) infusions of anitgenic material (blood) should be given, one about 8 weeks before the kid is due and a second infusion about two weeks after the first infusion. About 5 ml of blood or antigenic material is sufficient.
Teat Infusion Cannula can be obtained through a Veterinarian or Vets supply house. The purpose for the two infusions about 2 wweks apart is to first sensitize the animals immune system and the second one is to challenge it. Any addtional infusions probably have little added value and may increase the risk of a mastitis infection in the udder.
Note: Athough antibodies directed against human blood cells that might have formed in these first experiments are too large to be absorbed in the human gastrointestinal tract, the main reason for using a colonic or mammary gland infusion is the more efficient use of the chicken or goats immune system to produce a potent immunized egg or milk that has only positive effects (antibodies and transfer factors directed only against the pathogens and viruses) and eliminating all risk of unnecessary negative effects such as antibodies directed against human blood cells.
A series of articles by Anthony Di Fabio was in Part 3, called Universal Oral Vaccine - The Immune Milk Saga in the October, 2001, issue of The Townsend Letter for Doctors and Patients.
Several key figures in the history of transfer factor are written about in the article including the late Herb Saunders, former Congressman Berkeley Bedell, who says he was cured of Lyme disease, David Bergsma and Harry Willett of Quantum Research who once made the transfer factor for NK911 and now for Biomune.
In part of the article, Di Fabio suggsted the reader buy his own nanny goat or cow and immunize the animal when pregnant with a intermammary gland infusion of the persons own blood or other antigenic material. He reports on persons who treated Multiple Sclerosis successfully by drinking personal immunized milk/colostrum.
Some of the recommendations in the article are different than what Herb Saunders told me several years ago when he discussed how this was done. For example, I believe two infusions in the udder (about 2 weeks apart) of the pregnant animal are sufficient and not need be done weekly as suggested in the article.
For more information, you can obtain a copy of The October issue of The Townsend Letter issue #219 by calling them at 360-385-6021 or sending $9.00 to Townsend Letter, 911 Tyler St, Pt. Townsend, WA 98368 website: www.tldp.com
Anthony DiFabio who wrote the series of articles on the oral vaccines also has a website at www.arthritistrust.org.
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